Sr. Scientist, Cell Therapy In Vivo
12-month contract
Hybrid in Gaithersburg, MD - up to 2 days/week WFH
Responsibilities:
- Contributes primarily to running in vivo experiments and their designs, performs independent data analysis, and provides interpretations.
- Proficient in mice handling and procedures like iv infusion, tumor implantation and tissue processing
- Supports a team and works collaboratively to ensure efficient relay of information and forward translation of data.
- Maintains a well-developed understanding of drug discovery approaches and applies broader functional knowledge to support diverse project groups within the department.
- Assesses and reports data with minimal guidance, ensuring clarity and understanding of its implications within the overall context of drug discovery.
- Provides technical instruction to the team and allocates administrative tasks where possible.
- Shares relevant external published papers with peers.
- Communicates and shares information across distinct projects within the bioscience function and other departments.
- Ensures compliance with Good Laboratory Practice (GLP), Safety, Health and Environment (SHE) standards, and all other relevant internal AstraZeneca standards and external regulations.
Qualifications:
- PhD in Immunology or an equivalent field and/or professional certifications, with 0-3 years of post-doctoral training in immunology, T cell biology, and in vivo procedures.
- MS degree with 3-5 years of experience will also be considered.
- Proficiency in cell culture of established cell lines and primary human immune cells.
- Hands-on expertise in T-cell functional characterization assays, such as in vitro cytotoxicity, proliferation, and cytokine measurement.
- Well-developed understanding and expertise in molecular and cellular biology of immune cells, including the design and performance of functional assays, and cell transfection/transduction.
- Familiarity with multi-parameter flow cytometry, including immunostaining, acquisition, and analysis.
